Detecting Unique Spectral Fingerprints in Cough Sounds for Diagnosing Respiratory Diseases

Introduction:
Coughing is a common symptom associated with various illnesses, including COVID-19. Researchers are investigating the potential of using cough sound signals for a cost-effective method of disease diagnosis. Unlike traditional diagnostic methods, which are often expensive and require specialized personnel, smartphone-based cough analysis offers a more accessible alternative.

Objective:

To examine the feasibility of using acoustic analysis of cough sounds for diagnosing respiratory ailments, including COVID-19, pneumonia, and asthma.

Methods:

Cough Sample Collection Acoustic Analysis Machine Learning
• Analyzed cough sounds from 1183 COVID-19-positive patients.
• Compared with 341 non-COVID-19 cough samples.
Distinguished between coughs associated with pneumonia and asthma.
• Optimized frequency ranges to identify specific frequency bands.
• Conducted statistical separability tests to validate findings
• Used linear discriminant analysis and k- nearest neighbors classifiers.
• Confirmed distinct frequency bands in cough signal power spectra associated with different respiratory diseases.

Results:

Frequency Bands Identification

Specific frequency bands were correlated with each respiratory ailment.

Validation

Statistical tests and machine learning algorithms confirmed the presence of unique acoustic signatures for each disease.

Conclusion:

Acoustic signatures in cough sounds could revolutionize the classification and diagnosis of respiratory diseases.

This method offers a cost-effective and widely available healthcare tool for disease detection.

To know more: https://doi.org/10.1038/s41598-023-50371-2

Reference: Ghrabli S, et al. Identifying unique spectral fingerprints in cough sounds for diagnosing respiratory ailments. Scientific Reports. 2024 Jan 5;14(1):593.